ANNEX G Biological effects at low radiation doses
ثبت نشده
چکیده
I. CELLULAR EFFECTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 A. DESIGNATION OF LOW DOSES AND LOW DOSE RATES . . . . . . . . . 77 1. Physical factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 2. Biological approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 B. DAMAGE TO DNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 1. Dose response for low-LET radiation . . . . . . . . . . . . . . . . . . . . . . . . . 80 2. Dose response for high-LET radiation . . . . . . . . . . . . . . . . . . . . . . . . 81 3. Influence of track structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 C. CELLULAR DAMAGE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 1. Chromosome aberrations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 2. Cell transformation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 3. Mutagenesis in somatic cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 D. SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
منابع مشابه
Radiation hormesis and adoptive response induced by low doses of limiting radiation
Ionizing radiation has long been known to produce detrimental biological effects. Although these harmful effects are the results of high doses of exposure, some other maladies such as mutation and cancer seems to be induced at low doses of exposure. In recent decades, however, some pioneer scientists have indicated that ionizing radiation like many other essential agents has toxic effects ...
متن کاملA Novel Biological Dosimetry Method for Monitoring Occupational Radiation Exposure in Diagnostic and Therapeutic Wards: From Radiation Dosimetry to Biological Effects
Background and Objective: Professional radiation workers are occupationally exposed to long-term low levels of ionizing radiation. Occupational health hazards from radiation exposure, in a large occupational segment of the population, are of special concern. Biological dosimetry can be performed in addition to physical dosimetry with the aim of individual dose assessment and biological effects....
متن کاملAn in-vivo study on the energy dependence of X-ray biological effectiveness
Background: The International Commission on Radiological Protection (ICRP) has attributed the same relative risk for X and gamma radiations of all energies. Several studies have proven that the biological effect of low energy photon is more than that of higher ones. The assessment of risks is important due to the wide use of low energy X-rays for mammography screening and other diagnostic appli...
متن کاملThe biological effects induced by high-charged and energy particles and its application in cancer therapy
The radiobiological effects of high atomic number and energy (HZE particles) ion beams are of interest for radioprotection in space and tumor radiotherapy. Space radiation mainly consists of heavy charged particles from protons to iron ions, which is distinct from common terrestrial forms of radiation. HZE particles pose a significant cancer risk to astronauts on prolonged space missions. With ...
متن کاملPoor Understanding of Radiation Profiles in Deep Space Causes Inaccurate Findings and Misleading Conclusions
The radiation environment in deep space, where astronauts are behind the shelter provided by the Earth’s magnetosphere, is a major health concern. Galactic cosmic rays (GCR) and solar particle events (SPE) are two basic sources of space radiation in the solar system. The health risks of exposure to high levels of space radiation can be observed either as acute and delayed effects. Zhang et al. ...
متن کامل